ResearcherHarvard UniversityActive in the last 2 years
Rakesh K. Jain
Matched on ORCID iD 0000-0001-7571-3548; OpenAlex author ID A5015585176, A5157844125; NIH RePORTER profile ID 1871279. Sources: OpenAlex.
Their work
- Papers
- 10 (first author 0, last author 4)
- Trials
- 0
- Grants
- 2
- Labs led
- 1
- Collaborators
- 38
2014: 1 paper · 2015: 1 paper · 2016: 2 papers · 2017: 1 paper · 2018: none · 2019: 1 paper · 2020: 1 grant · 2021: 1 grant · 2022: 1 paper · 2023: 1 paper · 2024: none · 2025: 2 papers
Papers 10
- Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer. Co-author DOI 10.1016/j.immuni.2025.06.005↗
- IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against pancreatic cancer in mice with obesity. Last author DOI 10.1136/jitc-2024-011404↗
- Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic… Last author DOI 10.1158/1078-0432.ccr-22-1630↗
- Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment. Co-author DOI 10.1038/s41588-022-01134-8↗
- Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical… Co-author DOI 10.1001/jamaoncol.2019.0892↗
- Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma. Last author DOI 10.1158/1078-0432.ccr-17-0256↗
- Noninvasive Assessment of Losartan-Induced Increase in Functional Microvasculature and Drug Delivery in Pancreatic Ductal Adenocarcinoma. Co-author DOI 10.1016/j.tranon.2016.07.004↗
- Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. Last author DOI 10.1158/2159-8290.cd-15-1177↗
- Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. Co-author DOI 10.1371/journal.pone.0141392↗
- A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine followed by early surgery for resectable … Co-author DOI 10.1016/j.ijrobp.2014.03.034↗
Grants 2
Closest collaborators
The 25 strongest of 38 by collab_strength@1: shared papers, trials and grants, recent and small-team work weighing most.
- Dai Fukumura · 4 shared papers, 1 shared grant, 2015–2025 · strength 0.95
- Grant Reengineering obesity-induced abnormal microenvironment to improve PDAC treatment R01CA208205↗
- Paper IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against… DOI 10.1136/jitc-2024-011404↗
- Paper Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Can… DOI 10.1158/1078-0432.ccr-22-1630↗
- Yves Boucher · 6 shared papers, 1 shared grant, 2014–2023 · strength 0.83
- Grant Reprogramming PDAC tumor microenvironment to improve immunotherapy U01CA224348↗
- Paper Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Can… DOI 10.1158/1078-0432.ccr-22-1630↗
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Mikaël J. Pittet · 2 shared papers, 1 shared grant, 2021–2025 · strength 0.83
- Grant Reprogramming PDAC tumor microenvironment to improve immunotherapy U01CA224348↗
- Paper IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against… DOI 10.1136/jitc-2024-011404↗
- Paper Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Can… DOI 10.1158/1078-0432.ccr-22-1630↗
- Dan Gabriel Duda · 4 shared papers, 2014–2025 · strength 0.48
- Paper IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against… DOI 10.1136/jitc-2024-011404↗
- Paper Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Can… DOI 10.1158/1078-0432.ccr-22-1630↗
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Nilesh P. Talele · 3 shared papers, 2019–2025 · strength 0.45
- Paper IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against… DOI 10.1136/jitc-2024-011404↗
- Paper Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Can… DOI 10.1158/1078-0432.ccr-22-1630↗
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Theodore Sunki Hong · 4 shared papers, 2014–2023 · strength 0.29
- Paper Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Can… DOI 10.1158/1078-0432.ccr-22-1630↗
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- David P. Ryan · 4 shared papers, 2014–2023 · strength 0.29
- Paper Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Can… DOI 10.1158/1078-0432.ccr-22-1630↗
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- Jennifer Yon-Li Wo · 3 shared papers, 2014–2023 · strength 0.24
- Paper Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Can… DOI 10.1158/1078-0432.ccr-22-1630↗
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Paper A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine f… DOI 10.1016/j.ijrobp.2014.03.034↗
- Hao Liu · 4 shared papers, 2015–2017 · strength 0.19
- Paper Noninvasive Assessment of Losartan-Induced Increase in Functional Microvasculature and Drug Delivery in Pancreatic Duct… DOI 10.1016/j.tranon.2016.07.004↗
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- Paper Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. DOI 10.1371/journal.pone.0141392↗
- Dig Bijay Mahat · 1 shared paper, 2025 · strength 0.19
- Phillip A. Sharp · 1 shared paper, 2025 · strength 0.19
- Carlos F. Fernandez-del Castillo · 2 shared papers, 2014–2023 · strength 0.18
- Paper Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Can… DOI 10.1158/1078-0432.ccr-22-1630↗
- Paper A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine f… DOI 10.1016/j.ijrobp.2014.03.034↗
- Cristina Rosa Ferrone · 3 shared papers, 2016–2019 · strength 0.15
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- Paper Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. DOI 10.1158/2159-8290.cd-15-1177↗
- Mari A. Mino-Kenudson · 1 shared paper, 2023 · strength 0.14
- João Incio · 3 shared papers, 2015–2017 · strength 0.14
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- Paper Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. DOI 10.1371/journal.pone.0141392↗
- Paper Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. DOI 10.1158/2159-8290.cd-15-1177↗
- Vikram Deshpande · 3 shared papers, 2014–2017 · strength 0.13
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- Paper Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. DOI 10.1371/journal.pone.0141392↗
- Paper A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine f… DOI 10.1016/j.ijrobp.2014.03.034↗
- Janet E. Murphy · 2 shared papers, 2017–2019 · strength 0.11
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- Carlos Fernández-del Castillo · 2 shared papers, 2017–2019 · strength 0.11
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- Keith D. Lillemoe · 2 shared papers, 2017–2019 · strength 0.11
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- Lawrence Scott Blaszkowsky · 2 shared papers, 2014–2019 · strength 0.09
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Paper A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine f… DOI 10.1016/j.ijrobp.2014.03.034↗
- Eunice Lee Kwak · 2 shared papers, 2014–2019 · strength 0.09
- Paper Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanc… DOI 10.1001/jamaoncol.2019.0892↗
- Paper A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine f… DOI 10.1016/j.ijrobp.2014.03.034↗
- Theodoros P. Michelakos · 2 shared papers, 2016–2017 · strength 0.09
- Paper Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreat… DOI 10.1158/1078-0432.ccr-17-0256↗
- Paper Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. DOI 10.1158/2159-8290.cd-15-1177↗
- David Tsai Ting · 1 shared paper, 2019 · strength 0.06
- Jason Edward Faris · 1 shared paper, 2019 · strength 0.06
- Motaz Qadan · 1 shared paper, 2019 · strength 0.06
How to reach this person
A chain of introductions through people who have published, run trials or held grants together (warm_path@1: fewest links first, then the strongest). Built from public records only; no contact details are kept.