Pancreatic Cancer Research

ResearcherHarvard UniversityActive in the last 2 years

Rakesh K. Jain

Matched on ORCID iD 0000-0001-7571-3548; OpenAlex author ID A5015585176, A5157844125; NIH RePORTER profile ID 1871279. Sources: OpenAlex.

Their work

Papers
10 (first author 0, last author 4)
Trials
0
Grants
2
Labs led
1
Collaborators
38
Papers, trials and grants by year

2014: 1 paper · 2015: 1 paper · 2016: 2 papers · 2017: 1 paper · 2018: none · 2019: 1 paper · 2020: 1 grant · 2021: 1 grant · 2022: 1 paper · 2023: 1 paper · 2024: none · 2025: 2 papers

Papers 10

  1. Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer. Co-author DOI 10.1016/j.immuni.2025.06.005↗
  2. IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against pancreatic cancer in mice with obesity. Last author DOI 10.1136/jitc-2024-011404↗
  3. Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic… Last author DOI 10.1158/1078-0432.ccr-22-1630↗
  4. Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment. Co-author DOI 10.1038/s41588-022-01134-8↗
  5. Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical… Co-author DOI 10.1001/jamaoncol.2019.0892↗
  6. Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma. Last author DOI 10.1158/1078-0432.ccr-17-0256↗
  7. Noninvasive Assessment of Losartan-Induced Increase in Functional Microvasculature and Drug Delivery in Pancreatic Ductal Adenocarcinoma. Co-author DOI 10.1016/j.tranon.2016.07.004↗
  8. Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. Last author DOI 10.1158/2159-8290.cd-15-1177↗
  9. Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. Co-author DOI 10.1371/journal.pone.0141392↗
  10. A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine followed by early surgery for resectable … Co-author DOI 10.1016/j.ijrobp.2014.03.034↗

Grants 2

  1. Reprogramming PDAC tumor microenvironment to improve immunotherapy U01CA224348↗
  2. Reengineering obesity-induced abnormal microenvironment to improve PDAC treatment R01CA208205↗

Closest collaborators

The 25 strongest of 38 by collab_strength@1: shared papers, trials and grants, recent and small-team work weighing most.

  1. Dai Fukumura · 4 shared papers, 1 shared grant, 2015–2025 · strength 0.95
  2. Yves Boucher · 6 shared papers, 1 shared grant, 2014–2023 · strength 0.83
  3. Mikaël J. Pittet · 2 shared papers, 1 shared grant, 2021–2025 · strength 0.83
  4. Dan Gabriel Duda · 4 shared papers, 2014–2025 · strength 0.48
  5. Nilesh P. Talele · 3 shared papers, 2019–2025 · strength 0.45
  6. Theodore Sunki Hong · 4 shared papers, 2014–2023 · strength 0.29
  7. David P. Ryan · 4 shared papers, 2014–2023 · strength 0.29
  8. Jennifer Yon-Li Wo · 3 shared papers, 2014–2023 · strength 0.24
  9. Hao Liu · 4 shared papers, 2015–2017 · strength 0.19
  10. Dig Bijay Mahat · 1 shared paper, 2025 · strength 0.19
  11. Phillip A. Sharp · 1 shared paper, 2025 · strength 0.19
  12. Carlos F. Fernandez-del Castillo · 2 shared papers, 2014–2023 · strength 0.18
  13. Cristina Rosa Ferrone · 3 shared papers, 2016–2019 · strength 0.15
  14. Mari A. Mino-Kenudson · 1 shared paper, 2023 · strength 0.14
  15. João Incio · 3 shared papers, 2015–2017 · strength 0.14
  16. Vikram Deshpande · 3 shared papers, 2014–2017 · strength 0.13
  17. Janet E. Murphy · 2 shared papers, 2017–2019 · strength 0.11
  18. Carlos Fernández-del Castillo · 2 shared papers, 2017–2019 · strength 0.11
  19. Keith D. Lillemoe · 2 shared papers, 2017–2019 · strength 0.11
  20. Lawrence Scott Blaszkowsky · 2 shared papers, 2014–2019 · strength 0.09
  21. Eunice Lee Kwak · 2 shared papers, 2014–2019 · strength 0.09
  22. Theodoros P. Michelakos · 2 shared papers, 2016–2017 · strength 0.09
  23. David Tsai Ting · 1 shared paper, 2019 · strength 0.06
  24. Jason Edward Faris · 1 shared paper, 2019 · strength 0.06
  25. Motaz Qadan · 1 shared paper, 2019 · strength 0.06

How to reach this person

A chain of introductions through people who have published, run trials or held grants together (warm_path@1: fewest links first, then the strongest). Built from public records only; no contact details are kept.