Pancreatic Cancer Research

ResearcherBeth Israel Deaconess Medical CenterActive in the last 2 years

Raghu Kalluri

Matched on ORCID iD 0000-0002-2190-547X; OpenAlex author ID A5004654560; NIH RePORTER profile ID 1858925. Sources: OpenAlex.

Their work

Papers
31 (first author 0, last author 22)
Trials
0
Grants
7
Labs led
2
Collaborators
111
Papers, trials and grants by year

2014: 1 paper, 1 grant · 2015: 2 papers · 2016: 1 paper · 2017: 4 papers, 1 grant · 2018: 2 papers · 2019: 1 grant · 2020: 1 paper · 2021: 3 papers, 1 grant · 2022: 4 papers, 1 grant · 2023: 2 papers · 2024: 2 papers · 2025: 5 papers, 1 grant · 2026: 4 papers, 1 grant

Papers 31

  1. Pancreatic ductal adenocarcinoma: The Vision of Heracles. Co-author DOI 10.1016/j.ccell.2026.07.014↗
  2. Oncogenic KRAS Regulates Secretion of Extracellular Vesicles and Surface Membrane Charge via Regulation of Phosphatidylserine in Pancreatic Cancer. Last author DOI 10.1021/acsnano.6c08263↗
  3. Oncogenic Kras targeting with MRTX1133 or Daraxonrasib specifically synergize with anti-CTLA4 to promote anti-tumor immunity in pancreatic cancer. Last author DOI 10.1038/s41467-026-75960-3↗
  4. CDK8 remodels the tumor microenvironment and promotes resistance to KRAS G12D inhibitors and daraxonrasib in PDAC. Last author DOI 10.1038/s44318-026-00854-5↗
  5. Engineered exosomes with Kras G12D specific siRNA in pancreatic cancer: a phase I study with immunological correlates. Last author DOI 10.1038/s41467-025-63718-2↗
  6. Durotaxis is a driver and potential therapeutic target in lung fibrosis and metastatic pancreatic cancer. Co-author DOI 10.1038/s41556-025-01697-8↗
  7. Genetics and biology of pancreatic ductal adenocarcinoma. Co-author DOI 10.1101/gad.351863.124↗
  8. An allele-agnostic mutant-KRAS inhibitor suppresses tumor maintenance signals and reprograms tumor immunity in pancreatic cancer. Co-author DOI 10.1126/scitranslmed.adt5511↗
  9. Sonic hedgehog inhibitor suppresses carcinoma associated fibroblasts to prime Gemcitabine/Nab-Paclitaxel and anti-CTLA4 immunotherapy as sequential first-line … Co-author DOI 10.64898/2025.12.14.25342225↗
  10. Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Co-author DOI 10.1038/s41591-023-02694-w↗
  11. Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer. Last author DOI 10.1126/science.adh4567↗
  12. KRAS G12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells. Last author DOI 10.1016/j.ccell.2023.07.002↗
  13. Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells. Last author DOI 10.1016/j.devcel.2023.07.025↗
  14. Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer. Last author DOI 10.1016/j.ccell.2022.06.011↗
  15. Author Correction: Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Last author DOI 10.1038/s41586-022-05062-9↗
  16. Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression. Co-author DOI 10.1136/gutjnl-2021-324994↗
  17. Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer. Last author DOI 10.1158/2159-8290.cd-20-1484↗
  18. Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer. Last author DOI 10.1016/j.ccell.2021.02.007↗
  19. Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer. Last author DOI 10.1016/j.celrep.2021.108990↗
  20. Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic Kras G12D in pancreatic cancer. Last author DOI 10.26508/lsa.202000875↗
  21. Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer. Co-author DOI 10.1158/2159-8290.cd-19-0597↗
  22. Generation and testing of clinical-grade exosomes for pancreatic cancer. Last author DOI 10.1172/jci.insight.99263↗
  23. Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. Last author DOI 10.15252/emmm.201809085↗
  24. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Last author DOI 10.1038/nature22341↗
  25. Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer. Last author DOI 10.1038/ncomms15095↗
  26. Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer. Last author DOI 10.1080/15384047.2017.1281499↗
  27. Multiple antibodies identify glypican-1 associated with exosomes from pancreatic cancer cells and serum from patients with pancreatic cancer Last author DOI 10.1101/145706↗
  28. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Co-author DOI 10.1038/nm.4082↗
  29. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Last author DOI 10.1038/nature14581↗
  30. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Last author DOI 10.1038/nature16064↗
  31. Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer. Last author DOI 10.1074/jbc.c113.532267↗

Grants 7

  1. Biology and Function of Exosomes in Cancer R35CA263815↗
  2. Core C-Computational Core P01CA117969↗
  3. Mechanisms associated with organotropic metastasis R01CA252729↗
  4. Exosomes in Cancer Therapy R01CA213233↗
  5. Mechanisms of Alcohol Initiation of Chronic Pancreatic Diseases R21AA026462↗
  6. Employing mouse models to translate early detection of pancreas cancer R01CA195733↗
  7. Role of Fibroblasts, Myeloid Cells and Matrix in PDAC U01CA151925↗

Closest collaborators

The 25 strongest of 111 by collab_strength@1: shared papers, trials and grants, recent and small-team work weighing most.

  1. Kathleen M. McAndrews · 12 shared papers, 2018–2026 · strength 1.87
  2. Anirban Maitra · 8 shared papers, 1 shared grant, 2018–2026 · strength 1.82
  3. Krishnan K. Mahadevan · 7 shared papers, 2022–2026 · strength 1.15
  4. Sujuan Yang · 9 shared papers, 2017–2025 · strength 1.05
  5. Ronald Anthony Depinho · 3 shared papers, 1 shared grant, 2020–2025 · strength 0.99
  6. Yang Chen · 6 shared papers, 2018–2024 · strength 0.83
  7. Haoqiang Ying · 3 shared papers, 2023–2025 · strength 0.58
  8. Huamin Wang · 1 shared paper, 1 shared grant, 2022–2025 · strength 0.57
  9. Huamin Wang · 4 shared papers, 2017–2024 · strength 0.54
  10. Sónia A. Melo · 7 shared papers, 2014–2022 · strength 0.53
  11. Christoph Kahlert · 5 shared papers, 2014–2026 · strength 0.52
  12. Phillip Andrew Futreal · 1 shared paper, 1 shared grant, 2014–2025 · strength 0.49
  13. Timothy Paul Heffernan · 3 shared papers, 2023–2026 · strength 0.48
  14. Paola A. Guerrero · 3 shared papers, 2023–2026 · strength 0.48
  15. David R Piwnica-Worms · 2 shared papers, 1 shared grant, 2015–2022 · strength 0.46
  16. Julienne L. Carstens · 5 shared papers, 2015–2022 · strength 0.46
  17. Cyril Henri Benes · 1 shared grant, 2025 · strength 0.45
  18. Gerald C Chu · 1 shared grant, 2025 · strength 0.45
  19. NABEEL El-BARDEESY · 1 shared grant, 2025 · strength 0.45
  20. Ralph Weissleder · 1 shared grant, 2025 · strength 0.45
  21. Lewis C. Cantley · 1 shared grant, 2025 · strength 0.45
  22. Sarah P. Thayer · 1 shared grant, 2025 · strength 0.45
  23. James wesley Horner · 1 shared grant, 2025 · strength 0.45
  24. Tyler Jacks · 1 shared grant, 2025 · strength 0.45
  25. Craig D. Logsdon · 1 shared grant, 2019 · strength 0.40

How to reach this person

A chain of introductions through people who have published, run trials or held grants together (warm_path@1: fewest links first, then the strongest). Built from public records only; no contact details are kept.