Pancreatic Cancer Research

ResearcherJesse Brown VA Medical CenterActive in the last 2 years

Paul J. Grippo

ORCID-verified (high confidence, 0.95), identity_conf@1As of 6 November 2026

Matched on ORCID iD 0000-0002-6374-1282; OpenAlex author ID A5017375931; NIH RePORTER profile ID 7372587. Sources: funder_awards.

Their work

Papers
25 (first author 1, last author 4)
Trials
0
Grants
3
Labs led
2
Collaborators
66
Papers, trials and grants by year

2007: 1 grant · 2008: none · 2009: none · 2010: none · 2011: 3 papers · 2012: 3 papers · 2013: 1 paper · 2014: 1 paper · 2015: none · 2016: 2 papers, 1 grant · 2017: 3 papers · 2018: 3 papers · 2019: 4 papers · 2020: 1 paper · 2021: 2 papers · 2022: none · 2023: none · 2024: 1 paper · 2025: 1 paper · 2026: 1 grant

Papers 25

  1. Stromal fibrin shapes immune infiltration landscape of pancreatic ductal adenocarcinoma. Co-author DOI 10.1016/j.biomaterials.2025.123280↗
  2. Cell Membrane Fatty Acids and PIPs Modulate the Etiology of Pancreatic Cancer by Regulating AKT. Last author DOI 10.3390/nu17010150↗
  3. Mixed Lineage Kinase 3 phosphorylates prolyl-isomerase PIN1 and potentiates GLI1 signaling in pancreatic cancer development. Co-author DOI 10.1016/j.canlet.2021.04.015↗
  4. Role of stromal activin A in human pancreatic cancer and metastasis in mice. Co-author DOI 10.1038/s41598-021-87213-y↗
  5. Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer. Co-author DOI 10.1016/j.ajps.2020.02.003↗
  6. Knockout of Acinar Enriched microRNAs in Mice Promote Duct Formation But Not Pancreatic Cancer. Co-author DOI 10.1038/s41598-019-47566-x↗
  7. Animal Models: Challenges and Opportunities to Determine Optimal Experimental Models of Pancreatitis and Pancreatic Cancer. Co-author DOI 10.1097/mpa.0000000000001335↗
  8. TGFβ Blockade Augments PD-1 Inhibition to Promote T-Cell-Mediated Regression of Pancreatic Cancer. Co-author DOI 10.1158/1535-7163.mct-18-0850↗
  9. TM4SF18 is aberrantly expressed in pancreatic cancer and regulates cell growth. Co-author DOI 10.1371/journal.pone.0211711↗
  10. KRAS G12D and TP53R167H Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus scrofa Pigs. Co-author DOI 10.1038/s41598-018-30916-6↗
  11. Pancreatic cancer subtypes: a roadmap for precision medicine. First author DOI 10.1080/07853890.2018.1453168↗
  12. The Complexity of Omega-3 Fatty Acid Modulation of Signaling Pathways Related to Pancreatic Cancer. Last author DOI 10.2174/0929867324666170616111225↗
  13. miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal. Co-author DOI 10.1007/s10142-016-0512-1↗
  14. Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges. Co-author DOI 10.1152/ajpgi.00138.2017↗
  15. Canonical and alternative transcript expression of PAX6 and CXCR4 in pancreatic cancer. Co-author DOI 10.3892/ol.2017.5956↗
  16. Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia. Co-author DOI 10.1038/srep29133↗
  17. HDAC3 mediates smoking-induced pancreatic cancer. Co-author DOI 10.18632/oncotarget.6820↗
  18. Utilizing past and present mouse systems to engineer more relevant pancreatic cancer models. Last author DOI 10.3389/fphys.2014.00464↗
  19. Evaluating dietary compounds in pancreatic cancer modeling systems. Last author DOI 10.1007/978-1-62703-287-2_12↗
  20. Acinar-to-ductal metaplasia accompanies c-myc-induced exocrine pancreatic cancer progression in transgenic rodents. Co-author DOI 10.1002/ijc.27322↗
  21. The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation. Co-author DOI 10.1053/j.gastro.2011.10.026↗
  22. Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice. Co-author DOI 10.1136/gutjnl-2011-300821↗
  23. Apigenin down-regulates the hypoxia response genes: HIF-1α, GLUT-1, and VEGF in human pancreatic cancer cells. Co-author DOI 10.1016/j.jss.2010.10.041↗
  24. Collagen regulation of let-7 in pancreatic cancer involves TGF-β1-mediated membrane type 1-matrix metalloproteinase expression. Co-author DOI 10.1038/onc.2010.485↗
  25. Three-dimensional collagen I promotes gemcitabine resistance in pancreatic cancer through MT1-MMP-mediated expression of HMGA2. Co-author DOI 10.1158/0008-5472.can-10-1855↗

Grants 3

  1. Fibrin-laden tumor stroma as a novel immunomodulatory factor in pancreatic ductal adenocarcinoma R01CA304572↗
  2. N-3 Fatty Acid-Induced Akt Suppression: Chemoprevention for Pancreatic Neoplasia R01CA161283↗
  3. Evaluating Kras Oncogene Addiction in Pancreatic Precancer and Cancer AWARD pancan:2007-paul-j-grippo-phd-evaluating-kras-oncogene-addiction-in-pa

Closest collaborators

The 25 strongest of 66 by collab_strength@1: shared papers, trials and grants, recent and small-team work weighing most.

  1. Faraz Bishehsari · 2 shared papers, 1 shared grant, 2024–2026 · strength 1.38
  2. Taslim Ahmed Al-Hilal · 1 shared paper, 1 shared grant, 2025–2026 · strength 1.22
  3. Carolina Torres · 8 shared papers, 2018–2024 · strength 0.90
  4. Daniel R. Principe · 7 shared papers, 2014–2021 · strength 0.60
  5. Georgina E. Mancinelli · 4 shared papers, 2019–2024 · strength 0.47
  6. Hidayatullah G. Munshi · 6 shared papers, 2011–2019 · strength 0.31
  7. Ajay Nmn Rana · 3 shared papers, 2018–2021 · strength 0.27
  8. Megha Singhal · 2 shared papers, 2019–2024 · strength 0.26
  9. Mazharul Karim · 1 shared paper, 2025 · strength 0.22
  10. Navin Viswakarma · 2 shared papers, 2019–2021 · strength 0.21
  11. Sandeep Kumar · 2 shared papers, 2019–2021 · strength 0.21
  12. David W. Dawson · 2 shared papers, 2018–2021 · strength 0.19
  13. Lawrence B. Schook · 2 shared papers, 2018–2019 · strength 0.17
  14. Guido Eibl · 3 shared papers, 2012–2019 · strength 0.17
  15. Giulia Orsi · 1 shared paper, 2024 · strength 0.16
  16. Mouad Edderkaoui · 3 shared papers, 2012–2019 · strength 0.16
  17. Ana Clara P. Azevedo‐Pouly · 2 shared papers, 2017–2019 · strength 0.15
  18. Dhruvitkumar S. Sutaria · 2 shared papers, 2017–2019 · strength 0.15
  19. Jinmai Jiang · 2 shared papers, 2017–2019 · strength 0.15
  20. Thomas D. Schmittgen · 2 shared papers, 2017–2019 · strength 0.15
  21. Stephen Jacob Pandol · 2 shared papers, 2016–2019 · strength 0.13
  22. Brian T. DeCant · 2 shared papers, 2014–2016 · strength 0.12
  23. Rosa F. Hwang · 1 shared paper, 2021 · strength 0.12
  24. Barbara H. Jung · 1 shared paper, 2021 · strength 0.12
  25. Pier Cristoforo Giulianotti · 1 shared paper, 2021 · strength 0.12

How to reach this person

A chain of introductions through people who have published, run trials or held grants together (warm_path@1: fewest links first, then the strongest). Built from public records only; no contact details are kept.