Pancreatic Cancer Research

ResearcherBeckman Research InstituteActive in the last 2 years

Edwin Ramos Manuel

Matched on ORCID iD 0000-0002-4602-7060; OpenAlex author ID A5075582905; NIH RePORTER profile ID 10890689. Sources: OpenAlex.

Their work

Papers
9 (first author 1, last author 7)
Trials
0
Grants
3
Labs led
1
Collaborators
5
Papers, trials and grants by year

2016: 1 paper · 2017: none · 2018: none · 2019: 1 paper · 2020: 3 papers · 2021: 1 paper · 2022: 1 grant · 2023: none · 2024: 1 paper · 2025: 1 grant · 2026: 2 papers, 1 grant

Papers 9

  1. Dual inhibition of CSF-1R and IDO modulates the fibrotic and immunosuppressive tumor microenvironment in pancreatic ductal adenocarcinoma. Last author DOI 10.3389/fimmu.2026.1792483↗
  2. Precision Targeting of Heparan Sulfate Proteoglycans Broadly Dysregulates Survival Signaling and Metabolic Adaptation in Pancreatic Cancer Last author DOI 10.64898/2026.10.01.756059↗
  3. Tumor-Colonizing E. coli Expressing Both Collagenase and Hyaluronidase Enhances Therapeutic Efficacy of Gemcitabine in Pancreatic Cancer Models. Last author DOI 10.3390/biom14111458↗
  4. Collagenase-Expressing Salmonella Targets Major Collagens in Pancreatic Cancer Leading to Reductions in Immunosuppressive Subsets and Tumor Growth. Last author DOI 10.3390/cancers13143565↗
  5. Hyaluronidase-Expressing Salmonella Effectively Targets Tumor-Associated Hyaluronic Acid in Pancreatic Ductal Adenocarcinoma. Last author DOI 10.1158/1535-7163.mct-19-0556↗
  6. Targeting desmoplasia in pancreatic cancer as an essential first step to effective therapy. Last author DOI 10.18632/oncotarget.27745↗
  7. 5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma. Last author DOI 10.3389/fimmu.2020.00538↗
  8. Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice. Co-author DOI 10.1371/journal.pone.0221810↗
  9. Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer. First author DOI 10.1080/2162402x.2016.1160184↗

Grants 3

  1. Development of Microbial-Based Therapies to Suppress Macropinocytosis in Kras-Driven Cancers R01CA272732↗
  2. Microbial- based targeting of major extracellular matrix components for improved therapy of pancreatic cancer R01CA266472↗
  3. Lustgarten Foundation-AACR Career Development Award (John Robert Lewis): Edwin Manuel (therapeutic resistance and adaptation) AWARD lustgarten:2022-edwin-manuel-phd-lustgarten-foundation-aacr-career-develo

Closest collaborators

The 5 strongest of 5 by collab_strength@1: shared papers, trials and grants, recent and small-team work weighing most.

  1. Nancy D. Ebelt · 7 shared papers, 2020–2026 · strength 1.51
  2. Lara C. Avsharian · 3 shared papers, 2024–2026 · strength 0.89
  3. Don J. Diamond · 3 shared papers, 2016–2020 · strength 0.32
  4. Benjamin L. Johnson · 2 shared papers, 2019–2020 · strength 0.25
  5. Marcela d'Alincourt Salazar · 2 shared papers, 2016–2019 · strength 0.17

How to reach this person

A chain of introductions through people who have published, run trials or held grants together (warm_path@1: fewest links first, then the strongest). Built from public records only; no contact details are kept.