Pancreatic Cancer Research

ResearcherThe University of Texas MD Anderson Cancer CenterNo recent work listed

David A. Boothman

ORCID-verified (high confidence, 0.95), identity_conf@1As of 7 November 2026

Matched on ORCID iD 0000-0001-7474-9020; OpenAlex author ID A5016606481. Sources: funder_awards.

Their work

Papers
7 (first author 0, last author 5)
Trials
0
Grants
2
Labs led
1
Collaborators
18
Papers, trials and grants by year

2011: 1 paper · 2012: 1 grant · 2013: none · 2014: 1 grant · 2015: 4 papers · 2016: none · 2017: 2 papers

Papers 7

  1. Using a novel NQO1 bioactivatable drug, beta-lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer. Last author DOI 10.1002/jso.24624↗
  2. The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism. Co-author DOI 10.1074/jbc.m117.813923↗
  3. NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone. Last author DOI 10.1038/cddis.2014.564↗
  4. Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone. Last author DOI 10.1038/srep17066↗
  5. Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer. Co-author DOI 10.1158/0008-5472.can-15-0744↗
  6. Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone. Last author DOI 10.1186/s40170-015-0137-1↗
  7. Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy. Last author DOI 10.1158/1078-0432.ccr-10-1983↗

Grants 2

  1. Exploiting an NQO1 ‘kiss of death’ for pancreatic cancer therapy AWARD pancan:2014-david-boothman-phd-exploiting-an-nqo1-kiss-of-death-for-pan
  2. NQO1-mediated ‘Kiss of death’ Targeted Therapy for Pancreatic Cancer AWARD pancan:2012-david-boothman-phd-nqo1-mediated-kiss-of-death-targeted-the

Closest collaborators

The 18 strongest of 18 by collab_strength@1: shared papers, trials and grants, recent and small-team work weighing most.

  1. Zachary Moore · 4 shared papers, 2015 · strength 0.18
  2. Molly A. Silvers · 3 shared papers, 2015–2017 · strength 0.17
  3. Gaurab Chakrabarti · 3 shared papers, 2015 · strength 0.13
  4. Muhammad Shaalan Beg · 2 shared papers, 2017 · strength 0.13
  5. Matthew E. Merritt · 2 shared papers, 2017 · strength 0.13
  6. Rolf A. Brekken · 3 shared papers, 2011–2015 · strength 0.12
  7. Xiumei Huang · 1 shared paper, 2017 · strength 0.06
  8. Daniel A. Laheru · 1 shared paper, 2017 · strength 0.06
  9. Mary Topalovski · 1 shared paper, 2015 · strength 0.05
  10. Miao Wang · 1 shared paper, 2015 · strength 0.05
  11. Huamin Wang · 1 shared paper, 2015 · strength 0.05
  12. Agnieszka Katarzyna Witkiewicz · 1 shared paper, 2015 · strength 0.05
  13. Lewis C. Cantley · 1 shared paper, 2015 · strength 0.04
  14. Stanton L. Gerson · 1 shared paper, 2015 · strength 0.04
  15. Alec C. Kimmelman · 1 shared paper, 2015 · strength 0.04
  16. Costas Andreas Lyssiotis · 1 shared paper, 2015 · strength 0.04
  17. Long Shan Li · 1 shared paper, 2011 · strength 0.02
  18. Carlton C. Barnett · 1 shared paper, 2011 · strength 0.02

How to reach this person

A chain of introductions through people who have published, run trials or held grants together (warm_path@1: fewest links first, then the strongest). Built from public records only; no contact details are kept.