Pancreatic Cancer Research

ResearcherUSA Mitchell Cancer InstituteActive in the last 2 years

Ajay P. Singh

ORCID-verified (high confidence, 0.95), identity_conf@1As of 6 November 2026

Matched on ORCID iD 0000-0003-3492-6330; OpenAlex author ID A5000959667; NIH RePORTER profile ID 8895262. Sources: OpenAlex.

Their work

Papers
22 (first author 1, last author 15)
Trials
0
Grants
3
Labs led
1
Collaborators
19
Papers, trials and grants by year

2011: 2 papers · 2012: 1 paper · 2013: 1 paper, 1 grant · 2014: 2 papers · 2015: 3 papers · 2016: 3 papers · 2017: 2 papers · 2018: 1 paper, 1 grant · 2019: 1 paper · 2020: 3 papers · 2021: none · 2022: 1 paper, 1 grant · 2023: 1 paper · 2024: 1 paper

Papers 22

  1. Mitochondrial Translocase TOMM22 Is Overexpressed in Pancreatic Cancer and Promotes Aggressive Growth by Modulating Mitochondrial Protein Import and Function. Co-author DOI 10.1158/1541-7786.mcr-23-0138↗
  2. MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming. Last author DOI 10.15252/embr.202255643↗
  3. Detection of mitochondrial DNA mutations in circulating mitochondria-originated extracellular vesicles for potential diagnostic applications in pancreatic aden… Co-author DOI 10.1038/s41598-022-22006-5↗
  4. Hypoxia alters the release and size distribution of extracellular vesicles in pancreatic cancer cells to support their adaptive survival. Last author DOI 10.1002/jcb.29328↗
  5. Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer. Last author DOI 10.1074/jbc.ra119.011748↗
  6. Comprehensive Analysis of Expression, Clinicopathological Association and Potential Prognostic Significance of RABs in Pancreatic Cancer. Last author DOI 10.3390/ijms21155580↗
  7. Exosomal markers (CD63 and CD9) expression and their prognostic significance using immunohistochemistry in patients with pancreatic ductal adenocarcinoma. Last author DOI 10.21037/jgo.2018.07.02↗
  8. ETV4: an emerging target in pancreatic cancer. First author DOI 10.18632/oncoscience.471↗
  9. Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enz… Last author DOI 10.1038/bjc.2017.18↗
  10. Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward. Last author DOI 10.3390/ijms18040779↗
  11. p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling. Co-author DOI 10.1016/j.canlet.2015.10.028↗
  12. Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer. Last author DOI 10.1038/srep28446↗
  13. MYB Promotes Desmoplasia in Pancreatic Cancer through Direct Transcriptional Up-regulation and Cooperative Action of Sonic Hedgehog and Adrenomedullin. Last author DOI 10.1074/jbc.m116.732651↗
  14. Insights into the Role of microRNAs in Pancreatic Cancer Pathogenesis: Potential for Diagnosis, Prognosis, and Therapy. Last author DOI 10.1007/978-3-319-23730-5_5↗
  15. MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways. Last author DOI 10.1038/bjc.2015.252↗
  16. Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications. Last author DOI 10.18632/oncotarget.3784↗
  17. p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway. Co-author DOI 10.18632/oncotarget.2398↗
  18. Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer… Co-author DOI 10.2147/ijn.s61949↗
  19. An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and… Last author DOI 10.1074/jbc.m113.484576↗
  20. CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated ac… Co-author DOI 10.1074/jbc.m112.409581↗
  21. MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells. Last author DOI 10.1093/carcin/bgr223↗
  22. Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells. Last author DOI 10.1371/journal.pone.0021573↗

Grants 3

  1. A novel molecular cross-talk driving pancreatic cancer progression R01CA224306↗
  2. Targeting tumor-stromal interaction for pancreatic cancer therapy R01CA175772↗
  3. Myb, a key driver of pancreatic cancer progression and metastasis R21CA167137↗

Closest collaborators

The 19 strongest of 19 by collab_strength@1: shared papers, trials and grants, recent and small-team work weighing most.

  1. Seema Singh · 21 shared papers, 2011–2024 · strength 1.83
  2. Mohammad Aslam Khan · 10 shared papers, 2015–2024 · strength 1.22
  3. Sanjeev K. Srivastava · 14 shared papers, 2011–2023 · strength 0.87
  4. Moh'd M. Khushman · 8 shared papers, 2016–2022 · strength 0.75
  5. Arun Bhardwaj · 14 shared papers, 2011–2019 · strength 0.72
  6. Shashi Anand · 4 shared papers, 2020–2024 · strength 0.70
  7. Kunwar Somesh Vikramdeo · 3 shared papers, 2022–2024 · strength 0.57
  8. Santanu Dasgupta · 3 shared papers, 2020–2024 · strength 0.53
  9. Sachin Kumar Deshmukh · 3 shared papers, 2016–2023 · strength 0.37
  10. Girijesh Kumar Patel · 4 shared papers, 2017–2020 · strength 0.32
  11. Shafquat Azim · 3 shared papers, 2016–2023 · strength 0.31
  12. Sumit Arora · 7 shared papers, 2011–2016 · strength 0.29
  13. Mary C. Patton · 3 shared papers, 2017–2020 · strength 0.29
  14. Mary Oluwadamilola Haastrup · 1 shared paper, 2024 · strength 0.23
  15. Nikhil Tyagi · 4 shared papers, 2014–2016 · strength 0.22
  16. Martin J. Heslin · 1 shared paper, 2022 · strength 0.16
  17. Marcus Chuan Beng Tan · 1 shared paper, 2019 · strength 0.07
  18. Jayanth Panyam · 1 shared paper, 2014 · strength 0.04
  19. Gary Anthony Piazza · 1 shared paper, 2013 · strength 0.03

How to reach this person

A chain of introductions through people who have published, run trials or held grants together (warm_path@1: fewest links first, then the strongest). Built from public records only; no contact details are kept.