CSHL Course on Pancreatic Cancer

Abstract public domain (NIH RePORTER)

ABSTRACT Pancreatic Cancer Course Pancreatic cancer is one of the deadliest cancers ‐ tumors are often diagnosed at advanced stages of the disease and metastasize rapidly. This proposal seeks to continue an seven day intensive summer course on Pancreatic Cancer at Cold Spring Harbor Laboratory's Banbury Center on the north shore of Long Island, New York. This advanced discussion course for medical and graduate students, postdoctoral fellows and established investigators provides a comprehensive overview of clinical and biological aspects of pancreatic cancer with special emphasis on disease diagnosis and management, molecular pathways involved in tumor development and progression, mechanism‐based therapeutic strategies, advanced research tools, and ethical concerns. Discussion topics include: 1) Organ Overview: Anatomy, Physiology; 2) Clinical Aspects of Pancreatic Cancer: Diagnosis, Treatment; 3) Molecular Genetics of Pancreatic Cancer: Gene Signatures, Pre‐disposition Syndromes; 4) Pathobiology of Pancreatic Cancer: Pathways, Cell of Origin, Tumor Microenvironment; 5) Tools: Mouse Models, Imaging, Genomics, Proteomics, Metabolomics, Bioinformatics; 6) Therapeutics: Target Identification and Validation, Pre‐clinical Studies, Clinical Trials; and 7) Resources: Biobanks, Funding Strategies. The lead instructional team is chosen on the basis of their complementary contributions to and knowledge of the field. The lead instructors invite a series of distinguished lecturers who have made significant contributions to their fields and can provide up‐to‐the‐minute reports on current research. Because of the short duration of the courses, senior, as well as junior, individuals can attend and receive an intense period of training in an environment remote from other demands on their time and attention with ample opportunities for small group discussion and one‐on‐one mentoring.

Public health relevance public domain (NIH RePORTER)

LAY NARRATIVE Pancreatic Cancer Course Pancreatic cancer is one of the deadliest cancers ‐ tumors are often diagnosed at advanced stages of the disease and metastasize rapidly. This Cold Spring Harbor annual short course offers a comprehensive overview of clinical and biological aspects of pancreatic cancer with special emphasis on disease diagnosis and management, molecular pathways involved in tumor development and progression, mechanism‐based therapeutic strategies, advanced research tools, and ethical concerns. The course also promotes collaboration and exchange of ideas between faculty and trainees, and thus represent a significant and valuable investment towards accelerating cancer research by educating select cadres of researchers in the latest methods and concepts in these disciplines.