Journal articleCell Rep2021
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment.
- Journal
- Cell Rep
- Published
- 1 November 2021
- Citations
- 44
- Type
- Article
- License
- cc by
- Full text
- Open access, reuse-licensed (cc by)
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Grants 11
- Validation of WEE1 kinase as a clinical target in KRAS-mutant pancreatic cancer F30CA243253↗
- Targeting CDK4/6 for pancreatic cancer treatment F32CA221005↗
- Defining the contributions of WT RAS in RAS-mutant lung cancer F32CA232529↗
- Defining the roles of ERK MAPK in driving KRAS-mutant pancreatic cancer growth. F32CA239328↗
- Project 3: Mechanisms and therapeutic targeting of NRAS in melanoma P01CA203657↗
- Project 1: Overcoming Tumor-Induced Immune Suppression to Improve Responses to Immunotherapy P50CA196510↗
- Biological Activity of Ras Oncogenes R01CA042978↗
- Mechanisms of PAK1 activation, signaling and tumor resistance R01CA175747↗
- Targeting undruggable RAS for cancer treatment R35CA232113↗
- Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancers R37CA251877↗
- Identification of synthetic lethal interactors in pancreatic cancer U01CA199235↗