Journal articleSci Signal2025
Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer.
- Journal
- Sci Signal
- Published
- 30 September 2025
- Citations
- 6
- Type
- Article
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Grants 14
- Validation of WEE1 kinase as a clinical target in KRAS-mutant pancreatic cancer F30CA243253↗
- Mechanisms of YAP1-driven resistance to KRAS-G12C inhibition F31CA275260↗
- Defining the contributions of WT RAS in RAS-mutant lung cancer F32CA232529↗
- Defining the roles of ERK MAPK in driving KRAS-mutant pancreatic cancer growth. F32CA239328↗
- Identification of resistance mechanisms to direct KRAS inhibition in pancreatic cancer K22CA276632↗
- Mechanistic Basis for ERK in driving KRAS-dependent pancreatic cancer K99CA276700↗
- Project 3: Mechanisms and therapeutic targeting of NRAS in melanoma P01CA203657↗
- Project 1: Overcoming Tumor-Induced Immune Suppression to Improve Responses to Immunotherapy P50CA196510↗
- SToP Cancer SPORE: Administrative Core A P50CA257911↗
- Mechanistic Basis for ERK in driving KRAS-dependent pancreatic cancer R00CA276700↗
- Biological Activity of Ras Oncogenes R01CA042978↗
- Targeting undruggable RAS for cancer treatment R35CA232113↗
- Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancers R37CA251877↗
- Identification of synthetic lethal interactors in pancreatic cancer U01CA199235↗