Pancreatic Cancer Research

Clinical trialPhase 2Completed

Thalidomide in Treating Patients With Metastatic Neuroendocrine Tumors

Phase II Trial Of Thalidomide In Patients With Low Grade Neuroendocrine Tumors (Carcinoid and Islet Cell Cancers)

Outcome
Finished, no results posted
Phase
Phase 2
Status
Completed
Study type
Interventional
Start
March 2001
Expected end
December 2003
Sites
1
Sponsor
Other
Results posted
No
Last update
18 June 2013

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Brief summary public domain (ClinicalTrials.gov)

RATIONALE: Thalidomide may stop the growth of neuroendocrine tumors by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of thalidomide in treating patients who have metastatic neuroendocrine tumors.

Detailed description public domain (ClinicalTrials.gov)

OBJECTIVES: * Determine the safety and efficacy of thalidomide in patients with metastatic low-grade neuroendocrine tumors. OUTLINE: Patients receive oral thalidomide once daily on weeks 1-8. Courses repeat every 8 weeks in the absence of disease progression or unacceptable toxicity. PROJECTED ACCRUAL: A total of 14-25 patients will be accrued for this study.