Pancreatic Cancer Research

Clinical trialPhase 1Terminated

Endoscopic Ultrasound (EUS) Guided Ethanol With Paclitaxel Ablation for Pancreatic Mucinous Cystic Neoplasm

EUS Guided Ethanol With Paclitaxel Ablation for Pancreatic Mucinous Cystic Neoplasm

NCT01525706↗ ClinicalTrials.gov, retrieved 6 November 2026

Outcome
Stopped earlyPoor recruitment (Enrollment)
Phase
Phase 1
Status
Terminated
Study type
Interventional
Start
September 2012
Expected end
November 2016
Enrollment
1 participants
Sites
1
Primary outcomes
Efficacy: Cyst Resolution; Efficacy: Degree of Ablation
Sponsor
Other
Results posted
No
Last update
2 November 2016

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Brief summary public domain (ClinicalTrials.gov)

Pancreatic cysts are becoming diagnosed more frequently due to the increased use and sensitivity of imaging. A subset of these cysts are pre-cancerous, therefore suggested treatment is surgery for removal. However, surgery involves significant risks and emerging opinion suggests that not all cysts need to be surgically removed. An alternative therapy would be ideal, in particular for those where surgical risk outweighs the benefits of resection. Ethanol and paclitaxel ablation of pancreatic cysts may be a viable alternative to surgical resection. Our hypothesis is that ethanol with paclitaxel ablation is a safe and effective method for treatment in those with per-cancerous, mucinous pancreatic cysts.

Papers 4