Effect of Multi-Media Tool on Enrollment in Oncology Clinical Trials

Brief summary public domain (ClinicalTrials.gov)

The purpose of this research study is to test a touchscreen computer program, which allows patients to see information on a computer screen regarding cancer care, and specifically clinical trials. The purpose of this research is to help the investigators learn more about how to use technology in the medical setting to improve health outcomes.

Detailed description public domain (ClinicalTrials.gov)

Enrollment in therapeutic cancer trials remains low, and is especially challenging for patients with low health literacy. The purpose of this project is to pilot a multi-media technology intervention designed for patients with diverse health literacy skills with the aim of improving patient receptiveness, willingness, knowledge, self-efficacy, and positive attitudes regarding clinical trials. The intervention is comprised of multi-media touchscreen computer program components for clinical trial education and assessment of patient-reported outcomes. Patients presenting for their first oncology appointment were eligible. Patients viewed an interactive teaching video concerning clinical trials that was adapted from the National Institutes of Health. Validated surveys assessing receptiveness, willingness, knowledge, self-efficacy, and positive attitudes regarding clinical trials were administered before and after the test.

Intervention public domain (ClinicalTrials.gov)

Behavioral: Testing an interactive technology in a diverse health literary population. Enrollment in therapeutic cancer trials remains low, and is especially challenging for patients with low health literacy. We tested an interactive technology designed for patients with diverse health literacy skills aimed at improving patient receptiveness, willingness, knowledge, self-efficacy and positive attitudes regarding clinical trials.

Arm public domain (ClinicalTrials.gov)

Touchscreen Participants (): New lung, gastric and pancreatic cancer patients presenting to the University of Chicago outpatient oncology clinics, a large research institution located on Chicago's Southside, were identified for study accrual, using the electronic scheduling system.

Primary outcome public domain (ClinicalTrials.gov)

Clinical Trials Attitudes, Knowledge, and Interest. We hypothesized that our interactive educational tool would improve patient receptivity, willingness, knowledge, self-efficacy and positive attitudes regarding therapeutic cancer clinical trials through the use of patient-friendly technology in the immediate pre-visit period. Patients used the TT to self-administer 24 items from the Clinical Trial questionnaire developed by Jacobsen and colleagues measuring Receptivity (range: 1-5), Willingness (range: 1-5), Knowledge about cancer clinical trials (range: 0-6), Positive Attitudes toward clinical trials (range: 1-5), and Self-Efficacy (range: 1-5). A high score for each subscale represents a more favorable outcome. Time frame: Immediately after the visit..

Secondary outcome public domain (ClinicalTrials.gov)

Evaluate the Feasibility and Acceptability of Multi-media Technology.. Time frame: Immediately after the visit..

Secondary outcome public domain (ClinicalTrials.gov)

Clinical Trial Participation. Time frame: About 6 months after the interview with participant..

Eligibility public domain (ClinicalTrials.gov)

Inclusion Criteria: * Adult, English-speaking women and men * Newly diagnosed with lung, gastric or pancreatic cancer * Coming to the University of Chicago outpatient oncology clinics for their first oncology visit There are no Exclusion Criteria.

Enrollment public domain (ClinicalTrials.gov)

Enrollment: 120 participants (actual).

Posted results (ClinicalTrials.gov registry) · primary outcome public domain (ClinicalTrials.gov)

Clinical Trials Attitudes, Knowledge, and Interest [Immediately after the visit.]. Mean, units on a scale (Full Range). Receptivity: Touchscreen Participants (n=120): 4.6 (3 to 5). Willingness: Touchscreen Participants (n=120): 3.9 (2 to 5). Knowledge: Touchscreen Participants (n=120): 4.9 (1 to 6). Positive Attitude: Touchscreen Participants (n=120): 3.7 (2.6 to 4.9). Self-Efficacy: Touchscreen Participants (n=120): 4.3 (3.5 to 5). Analysis, Touchscreen Participants: p=.307; t-test, 2 sided; superiority. Analysis, Touchscreen Participants: p=.009; t-test, 2 sided; superiority. Analysis, Touchscreen Participants: p=<.001; t-test, 2 sided; superiority. Analysis, Touchscreen Participants: p=.004; t-test, 2 sided; superiority. Analysis, Touchscreen Participants: p=<.001; t-test, 2 sided; superiority.

Posted results (ClinicalTrials.gov registry) · secondary outcome public domain (ClinicalTrials.gov)

Evaluate the Feasibility and Acceptability of Multi-media Technology. [Immediately after the visit.]. Count Of Participants, Participants. Difficulty using the touchscreen-not at all, a little bit: Touchscreen Participants (n=109): 102. Overall rating of screen design-very good, excellent: Touchscreen Participants (n=109): 73. Have you used a computer within the past 12 mo-yes: Touchscreen Participants (n=109): 98. Have you ever used a touchscreen before-yes: Touchscreen Participants (n=109): 100. Difficulty using the touchscreen to view the video or learning program-not at all: Touchscreen Participants (n=109): 99. Overall rating of video-very good, excellent: Touchscreen Participants (n=109): 77. Overall rating of learning program-very good, excellent: Touchscreen Participants (n=109): 78. Did the video help you to better understand clinical trials-somewhat, quite a bit: Touchscreen Participants (n=109): 100. Did the learning program (NC) help you to better understand clinical trials-somewhat, quite a bit: Touchscreen Participants (n=109): 94. Overall rating of the amount of time you spent on this study, about right: Touchscreen Participants (n=109): 96. Rate your experience participating-a little better, a lot better than expected: Touchscreen Participants (n=109): 61.

Posted results (ClinicalTrials.gov registry) · secondary outcome public domain (ClinicalTrials.gov)

Clinical Trial Participation [About 6 months after the interview with participant.]. Number, Percentage of participants. Discussed clinical trials with a physician: Touchscreen Participants (n=120): 63. Offered a clinical trial among those who reported a discussion: Touchscreen Participants (n=120): 38. Enrolled in a clinical trial among those offered a clinical trial: Touchscreen Participants (n=120): 48.