Clinical trialPhase 1Completed
Safety and Feasibility of imILT Locally Advanced Pancreatic Cancer (LAPC)
Immunostimulating Interstitial Laser Thermotherapy in Patients With Locally Advanced Pancreatic Cancer: Results of a Prospective, Open, Non Comparative Study
- Outcome
- Finished, no results posted
- Phase
- Phase 1
- Status
- Completed
- Study type
- Interventional
- Start
- February 2016
- Expected end
- October 2021
- Enrollment
- 10 participants
- Sites
- 1
- Primary outcomes
- Number of participants with treatment-related adverse events as assessed by CTCAE v4.0
- Sponsor
- Other
- Results posted
- No
- Last update
- 21 April 2022
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Brief summary public domain (ClinicalTrials.gov)
10 Patients with Locally Advanced Pancreatic Cancer, no further responsive to neoadjuvant treatments but with a Stage-III disease will be submitted to imILT (Immunostimulating Interstitial Laser Thermotherapy). Safety and feasibility of imILT on LAPC will be evaluated as primary objective. Secondary objectives will be QoL after imILT, study of the immune reaction after imILT, oncological analysis of patients suffering from LAPC submitted to imILT.
Papers 6
- Builds on itLaser Treatment of Pancreatic Cancer with Immunostimulating Interstitial Laser Thermotherapy Protocol: Safety and Feasi… DOI 10.1016/j.jss.2020.10.027↗
- BackgroundChanges in immunocompetent cells after interstitial laser thermotherapy of breast cancer. DOI 10.1007/s00262-011-0992-8↗
- BackgroundResistance to tumour challenge after tumour laser thermotherapy is associated with a cellular immune response. DOI 10.1038/sj.bjc.6602718↗
- BackgroundHeat shock protein 70 (HSP70) after laser thermotherapy of an adenocarcinoma transplanted into rat liver. PMID 14666667↗
- BackgroundInterstitial laser thermotherapy of a rat liver adenocarcinoma. DOI 10.3233/xst-2002-00067↗
- BackgroundInterstitial laser treatment of malignant tumours: initial experience. DOI 10.1016/s0748-7983(96)91451-1↗