Clinical trialPhase 2Unknown
Niraparib in Metastatic Pancreatic Cancer After Previous Chemotherapy (NIRA-PANC): a Phase 2 Trial
- Outcome
- Outcome unknown
- Phase
- Phase 2
- Status
- Unknown
- Study type
- Interventional
- Start
- 22 January 2019
- Expected end
- 1 February 2025
- Enrollment
- 18 participants
- Sites
- 6
- Primary outcomes
- Objective Response Rate (ORR)
- Sponsor
- Other
- Results posted
- No
- Last update
- 19 May 2023
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Source text
Brief summary public domain (ClinicalTrials.gov)
The goal of this clinical research study is to learn if Niraparib can help to control metastatic pancreatic cancer. The safety of this drug will also be studied. Niraparib is FDA approved and commercially available for the treatment of ovarian cancer. Its use in this study is investigational.
Papers 2
- Builds on itNiraparib in pancreatic cancer with germline or somatic DNA damage repair (DDR) gene alterations (BRCA and beyond): a p… DOI 10.1093/oncolo/oyag225↗
- Builds on itCirculating Tumor Cell Subpopulations Predict Treatment Outcome in Pancreatic Ductal Adenocarcinoma (PDAC) Patients. DOI 10.3390/cells12182266↗