Clinical trialNAActive not recruiting
Electron Beam Intraoperative Radiation Therapy Following Chemoradiation in Patients With Pancreatic Cancer With Vascular Involvement
PACER (Pancreatic AdenoCarcinoma With Electron Intraoperative Radiation Therapy): A Phase II Study of Electron Beam Intraoperative Radiation Therapy Following Chemoradiation in Patients With Pancreatic Cancer With Vascular Involvement
- Outcome
- Ongoing
- Phase
- NA
- Status
- Active not recruiting
- Study type
- Interventional
- Start
- 19 March 2019
- Expected end
- 31 December 2027
- Enrollment
- 199 participants
- Sites
- 6
- Primary outcomes
- 2 Year Overall Survival
- Sponsor
- Other
- Results posted
- No
- Last update
- 14 July 2026
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Brief summary public domain (ClinicalTrials.gov)
This research study is studying an intervention as a possible treatment for pancreatic cancer.
Detailed description public domain (ClinicalTrials.gov)
In this research study, the investigators are researching how well IORT during surgery works in treating pancreatic cancer after 3-6 months of chemotherapy and external radiation therapy. IORT works by delivering radiation therapy to the tumor while reducing the amount of healthy tissue exposed to the radiation therapy. The investigators believe that the administration of IORT after 3-6 months of chemotherapy will help to stop the cancer cells from growing. The FDA (the U.S. Food and Drug Administration) has not approved IORT for this specific disease but it has been approved for other uses.