Clinical trialNAUnknown
The Therapeutic Evaluation(Both Short-term and Long-term Outcome) of Minimal Invasive Radical Antegrade Modular Pancreatosplenectomy for Left-sided Pancreatic Cancer Patients
Minimal Invasive Versus Open Radical Antegrade Modular Pancreatosplenectomy for Left-sided Pancreatic Cancer: a Randomized Controlled Trial
- Outcome
- Outcome unknown
- Phase
- NA
- Status
- Unknown
- Study type
- Interventional
- Start
- 1 July 2020
- Expected end
- 30 December 2024
- Enrollment
- 125 participants
- Sites
- 1
- Primary outcomes
- Posteroperative length of stay
- Sponsor
- Other
- Results posted
- No
- Last update
- 20 May 2022
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Brief summary public domain (ClinicalTrials.gov)
Pancreatic cancer is regarded as "the king of cancer". It is extremely malignant, with a low sensibility to chemotherapy and radiotherapy, and a poor prognosis. Surgical treatment is very important for pancreatic cancer. Radical antegrade modular pancreatosplenectomy (RAMPS) is a standard method for treating pancreatic cancer at the body and tail of pancreas. In the same surgical approach, the investigators are going to compare and discuss the advantages of laparoscopic and open RAMPS in the RCT study.
Detailed description public domain (ClinicalTrials.gov)
Open RAMPS is widely used now to treat pancreatic cancer at the body and tail of pancreas. Meanwhile, laparoscopic surgery is proved to have many advantages in other operations. According to primary retrospective study of open and laparoscopic RAMPS, there was no statistically significant difference in the long-term follow-up situations between these two groups, indicating the safety of both this two surgical approaches. The investigators would like to promote a prospective RCT study, to give more evidences of the superiority of laparoscopic RAMPS.
Papers 4
- Builds on itThe effect of minimally invasive or open radical antegrade modular pancreatosplenectomy on pancreatic cancer: A multice… DOI 10.3389/fonc.2022.965508↗
- BackgroundRadical antegrade modular pancreatosplenectomy versus standard procedure in the treatment of left-sided pancreatic canc… DOI 10.1186/s12893-017-0259-1↗
- BackgroundLaparoscopic radical antegrade modular pancreatosplenectomy for left-sided pancreatic cancer using the ligament of Trei… DOI 10.1007/s00464-017-5561-6↗
- BackgroundRole of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of the pancreas. DOI 10.1007/s00268-013-2254-8↗