Clinical trialNo phase (not a drug trial)Completed
Optic Nerve Sheath Diameter Difference Between Different Injection Volume
Effect of Normal Saline Injection Volume on Epidural Pressure and Optic Nerve Sheath Diameter
- Outcome
- Finished, no results posted
- Phase
- No phase (not a drug trial)
- Status
- Completed
- Study type
- Interventional
- Start
- 25 May 2020
- Ended
- 16 November 2020
- Enrollment
- 50 participants
- Sites
- 1
- Primary outcomes
- optic nerve sheath change during 4 time period
- Sponsor type
- Academic / other
- Results posted
- No
- Last update
- 18 November 2020
These fields come from the trial’s registry entry. A summary of its population, design, endpoints and results, each tied to a quote, has not been written for this trial yet.
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Brief summary public domain (ClinicalTrials.gov)
Valid method of indirect measurement of intracranial pressure is using optic nerve sheath diameter. Different volume of injection is known to affect the degree of increase of intracranial pressure. This study is desinged to measure the changes of optic nerve sheath diameter and cerebral oxygenation when different volume of normal saline was injected.
Detailed description public domain (ClinicalTrials.gov)
Previous study showed that different volume of injections (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia showed siginifiant increase of optic nerve sheath diameter in group of high volumes. Increase of ICP can result in harmful effect including reduced cerebral flow and oxygen saturation. Also, increase of ICP can cause headache, syncope and transient loss of visual acuity. The proven and valid method of measuring ICP indirectly is using optic nerve sheath diameter. This study was designed to examine the changes of optic nerve sheath diameter and cerebral oxygenation when different volume of normal saline was injected.