Clinical trialNAUnknown
Comparsion of WT and SNP Techniques of EUS-FNB in Pancreatic Solid Mass (WESP-PSM)
A Multicenter Prospective Clinical Study of Wet-suction Technique and Standard Negative Pressure Technique in EUS-FNB for the Diagnosis of Pancreatic Solid Mass
- Outcome
- Outcome unknown
- Phase
- NA
- Status
- Unknown
- Study type
- Interventional
- Start
- 1 December 2020
- Expected end
- 30 September 2022
- Enrollment
- 296 participants
- Sites
- 0
- Primary outcomes
- diagnostic sensitivity of WS technique and SNP technique by EUS-FNB; diagnostic specificity of WS technique and SNP technique by EUS-FNB
- Sponsor
- Other
- Results posted
- No
- Last update
- 27 November 2020
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Brief summary public domain (ClinicalTrials.gov)
The purpose of this study is to compare the diagnosis accuracy between of wet suction (WS) technique and standard negative pressure (SNP) technique in EUS-FNB by 22G EUS Procore fine needle biopsy(FNB)device for solid pancreatic lesions.
Detailed description public domain (ClinicalTrials.gov)
This is a multi-center, single-blind, randomized, controlled trial. two hundred and ninety six patients with solid pancreatic lesions referred for EUS guided fine needle biopsy will be randomly assigned to two groups. For group A which will be used with 22G EUS Procore fine needle biopsy device, the pass sequence is WS-SNP-WS-SNP technique. For group B with 22G EUS Procore fine needle biopsy device, the pass sequence is SNP-WS-SNP-WS. All procedures will be performed by experienced echo-endoscopists, and the patients and assessors (cytologists and pathologists) will be blinded during the entire study. The primary outcome measure is the diagnosis yield. Secondary outcome measures are specimen quality.
Papers 4
- BackgroundWet- versus dry-suction techniques for endoscopic ultrasound-guided fine-needle aspiration of solid lesions: a multicen… DOI 10.1055/a-1167-2214↗
- BackgroundComparison of 22G reverse-beveled versus standard needle for endoscopic ultrasound-guided sampling of solid pancreatic … DOI 10.1177/2050640615577533↗
- Background"Wet suction technique (WEST)": a novel way to enhance the quality of EUS-FNA aspirate. Results of a prospective, singl… DOI 10.1016/j.gie.2014.11.023↗
- BackgroundA prospective, comparative trial to optimize sampling techniques in EUS-guided FNA of solid pancreatic masses. DOI 10.1016/j.gie.2012.12.009↗