Clinical trialObsCompleted
Predicting Disease Progression and/or Recurrence in Cancer
Tumor Markers, Liquid Biopsies, and Patient Reported Outcomes in Metastatic Colorectal, Pancreas, Biliary, and Esophagogastric Cancers
- Outcome
- Finished, no results posted
- Phase
- Obs
- Status
- Completed
- Study type
- Observational
- Start
- 15 May 2019
- Expected end
- 19 October 2022
- Enrollment
- 159 participants
- Sites
- 1
- Primary outcomes
- Treatment Response at 1st Scan
- Sponsor
- Other
- Results posted
- No
- Last update
- 15 May 2026
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Brief summary public domain (ClinicalTrials.gov)
This is a prospective study addressing the challenge of predicting disease progression and/or recurrence in patients diagnosed with metastatic colorectal, pancreatobiliary, or esophagogastric cancer that are receiving anti-cancer therapy.
Detailed description public domain (ClinicalTrials.gov)
This research study is evaluating how patient-reported outcomes (e.g. symptoms, quality of life) and biomarkers compare to standard of care clinical assessments such as imaging and tumor markers in predicting the clinical outcomes (e.g. disease progression and survival) in patient populations with colorectal, pancreatobiliary, or esophagogastric cancer that are receiving anti-cancer therapy Massachusetts General Hospital Cancer Center * Patient reported outcomes will be collected through a series of self-administered questionnaires and blood draws will be used to obtain bio and tumor marker information. * Information will also be collected from the participants electronic medical record. * Tissue may be obtained for next-generation sequencing. * The study will conclude after participants are no longer receiving anti-cancer therapies. * It is expected that about 200 people will take part in this research study
Papers 1
- Registry-listed results paperPatient-Reported Outcomes, Tumor Markers, and Survival Outcomes in Advanced GI Cancer. DOI 10.1001/jamanetworkopen.2023.43512↗
The registry lists these as results papers; in a hand check of 27 such links about 78% reported the trial’s results, so read the paper before treating it as the outcome.