Clinical trialPhase 2Completed
TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma
Phase II Trial of TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma
- Outcome
- Finished, no results posted
- Phase
- Phase 2
- Status
- Completed
- Study type
- Interventional
- Start
- 1 March 2021
- Expected end
- 31 December 2024
- Enrollment
- 28 participants
- Sites
- 1
- Primary outcomes
- 16-week progression-free survival (PFS) rate
- Sponsor
- Other
- Results posted
- No
- Last update
- 18 July 2025
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Papers 12
- BackgroundRandomised phase II trial of irinotecan plus S-1 in patients with gemcitabine-refractory pancreatic cancer. DOI 10.1038/bjc.2016.436↗
- BackgroundPANCREOX: A Randomized Phase III Study of Fluorouracil/Leucovorin With or Without Oxaliplatin for Second-Line Advanced … DOI 10.1200/jco.2016.68.5776↗
- BackgroundA randomized phase II study of S-1 plus oral leucovorin versus S-1 monotherapy in patients with gemcitabine-refractory … DOI 10.1093/annonc/mdv603↗
- BackgroundNanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-… DOI 10.1016/s0140-6736(15)00986-1↗
- BackgroundRandomised phase II trial of S-1 plus oxaliplatin vs S-1 in patients with gemcitabine-refractory pancreatic cancer. DOI 10.1038/bjc.2015.103↗
- BackgroundS-1 as monotherapy or in combination with leucovorin as second-line treatment in gemcitabine-refractory advanced pancre… DOI 10.1634/theoncologist.2014-0223↗
- BackgroundSecond-line oxaliplatin, folinic acid, and fluorouracil versus folinic acid and fluorouracil alone for gemcitabine-refr… DOI 10.1200/jco.2013.53.6995↗
- BackgroundIncreased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. DOI 10.1056/nejmoa1304369↗
- BackgroundA multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-ref… DOI 10.1038/bjc.2013.408↗
- BackgroundA phase II trial of nab-Paclitaxel as second-line therapy in patients with advanced pancreatic cancer. DOI 10.1097/coc.0b013e3182436e8c↗
- BackgroundFOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. DOI 10.1056/nejmoa1011923↗
- BackgroundPhase II study of S-1 in patients with gemcitabine-resistant advanced pancreatic cancer. DOI 10.1007/s00280-010-1311-3↗