Clinical trialEPhase 1Suspended
Fecal Microbial Transplants for the Treatment of Pancreatic Cancer
Pilot Study Using Fecal Microbial Transplants in Patients With Pancreatic Cancer
- Outcome
- Stopped earlyPI request (Other)
- Phase
- EPhase 1
- Status
- Suspended
- Study type
- Interventional
- Start
- 14 December 2021
- Expected end
- 31 December 2026
- Enrollment
- 10 participants
- Sites
- 1
- Primary outcomes
- Incidence of adverse events
- Sponsor
- Other
- Results posted
- No
- Last update
- 22 May 2026
These are registry fields. A trial card, with population, design, endpoints and result direction each tied to a quote, is not in the data yet.
Ask this document
Answers come only from this document’s own text, as highlighted quotes. If it doesn’t say, you are told so instead of given a guess.
Try
Source text
Brief summary public domain (ClinicalTrials.gov)
This early phase I trial examines the safety and effects of fecal microbial transplants in treating patients with pancreatic cancer. scheduled for surgery to remove tumors. Fecal microbial transplant contains the normal microbes found in fecal (stool) material. Giving fecal microbial transplant may help control the disease.
Detailed description public domain (ClinicalTrials.gov)
PRIMARY OBJECTIVE: I. To assess the safety, tolerability, and feasibility of fecal microbiota transplantation (FMT) in resectable patients with pancreatic ductal adenocarcinoma (PDAC). SECONDARY OBJECTIVES: I. To assess changes in gut microbiome of PDAC patients after FMT. II. To assess changes in oral microbiome of PDAC patients after FMT. III. To assess changes in tumor microbiome of PDAC patients after FMT. IV. To determine immunological/molecular changes in the tumor after FMT. OUTLINE: Patients undergo FMT during colonoscopy. Patients also receive FMT capsules orally (PO) once weekly (QW) for 4 weeks in the absence of disease progression or unacceptable toxicity. Patients then undergo standard of care resection of tumor(s). After completion of study treatment, patients are followed up at 2 weeks and 30, 60, 90, and 180 days after surgery.