Clinical trialObsUnknown
Pharmacotyping of Pancreatic Patient-derived Organoids
Pharmacotyping of Patient-derived Pancreatic Cancer Organoids From Endoscopic Ultrasound-guided Biopsy as a Tool for Predicting Oncological Response
- Outcome
- Outcome unknown
- Phase
- Obs
- Status
- Unknown
- Study type
- Observational
- Start
- 1 July 2021
- Expected end
- 31 August 2025
- Enrollment
- 88 participants
- Sites
- 1
- Primary outcomes
- Measurement of organoid's response to therapy; Validation of patient's response to therapy; Comparison between organoid's and patient's response
- Sponsor
- Other
- Results posted
- No
- Last update
- 3 October 2024
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Papers 8
- BackgroundPatient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer. DOI 10.1097/sla.0000000000004200↗
- BackgroundOrganoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer. DOI 10.1158/2159-8290.cd-18-0349↗
- BackgroundSuccessful creation of pancreatic cancer organoids by means of EUS-guided fine-needle biopsy sampling for personalized … DOI 10.1016/j.gie.2017.12.032↗
- BackgroundDistinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. DOI 10.1084/jem.20162024↗
- BackgroundOrganoid models of human and mouse ductal pancreatic cancer. DOI 10.1016/j.cell.2014.12.021↗
- BackgroundIncreased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. DOI 10.1056/nejmoa1304369↗
- BackgroundFOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. DOI 10.1056/nejmoa1011923↗
- BackgroundNORDCAN--a Nordic tool for cancer information, planning, quality control and research. DOI 10.3109/02841861003782017↗