Pancreatic Cancer Research

Clinical trialPhase 1 / Phase 2Completed

A Study of AK112 in Advanced Malignant Tumors

A Phase Ib/II Study of AK112(PD-1 / VEGF Bispecific Antibody) in Combination With AK117(Anti-CD47 Antibody)With or Without Chemotherapy in Advanced Malignant Tumors

Outcome
Finished, no results posted
Phase
Phase 1 / Phase 2
Status
Completed
Study type
Interventional
Start
22 January 2022
Expected end
31 December 2025
Enrollment
154 participants
Sites
1
Primary outcomes
Number of patients with Adverse Events (AEs); Objective Response Rate (ORR)
Sponsor
Industry
Results posted
No
Last update
3 March 2026

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Brief summary public domain (ClinicalTrials.gov)

Phase Ib/II open label, multicenter study to evaluate the efficacy and safety of AK112 (anti-PD-1 and VEGF bispecific antibody) combined with AK117(Anti-CD47 Antibody)with or without chemotherapy in advanced malignant tumors