Clinical trialNAUnknown
Concurrent FOLFIRINOX Plus High Intensity Focused Ultrasound for Pancreatic Cancer
Therapeutic Efficacy and Safety of Concurrent FOLFIRINOX Plus HIFU for Locally Advanced/Borderline Resectable Pancreatic Cancer: A Prospective Single-center, Single-arm, Investigator-initiated, Open-labeled, Exploratory Clinical Trial
- Outcome
- Outcome unknown
- Phase
- NA
- Status
- Unknown
- Study type
- Interventional
- Start
- 9 August 2021
- Expected end
- December 2024
- Enrollment
- 60 participants
- Sites
- 1
- Primary outcomes
- 2-month Tumor Response; 4-month Tumor Response; 6-month Tumor Response; Percentage of subjects that were subject to surgical resection
- Sponsor
- Other
- Results posted
- No
- Last update
- 26 October 2022
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Papers 19
- Builds on itNon-thermal focused ultrasound with FOLFIRINOX for borderline resectable or locally advanced pancreatic cancer: An expl… DOI 10.1016/j.ejca.2026.116903↗
- BackgroundPrognostic Factors for Patients with Borderline Resectable or Locally Advanced Pancreatic Cancer Receiving Neoadjuvant … DOI 10.5009/gnl19182↗
- BackgroundNeoadjuvant modified FOLFIRINOX followed by postoperative gemcitabine in borderline resectable pancreatic adenocarcinom… DOI 10.1038/s41416-020-0867-x↗
- BackgroundNeoadjuvant FOLFIRINOX in Patients With Borderline Resectable Pancreatic Cancer: A Systematic Review and Patient-Level … DOI 10.1093/jnci/djz073↗
- BackgroundFOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer. DOI 10.1056/nejmoa1809775↗
- BackgroundTotal Neoadjuvant Therapy With FOLFIRINOX Followed by Individualized Chemoradiotherapy for Borderline Resectable Pancre… DOI 10.1001/jamaoncol.2018.0329↗
- BackgroundClinical Effectiveness and Potential Survival Benefit of US-Guided High-Intensity Focused Ultrasound Therapy in Patient… DOI 10.1055/a-0591-3386↗
- BackgroundIn vivo study of enhanced chemotherapy combined with ultrasound image-guided focused ultrasound (USgFUS) treatment for … DOI 10.1007/s00330-018-5355-9↗
- BackgroundLocally Advanced Pancreatic Cancer: Neoadjuvant Therapy With Folfirinox Results in Resectability in 60% of the Patients. DOI 10.1097/sla.0000000000001850↗
- BackgroundTherapeutic Effects of Microbubbles Added to Combined High-Intensity Focused Ultrasound and Chemotherapy in a Pancreati… DOI 10.3348/kjr.2016.17.5.779↗
- BackgroundSystematic Review of Resection Rates and Clinical Outcomes After FOLFIRINOX-Based Treatment in Patients with Locally Ad… DOI 10.1245/s10434-016-5373-2↗
- BackgroundFOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis. DOI 10.1016/s1470-2045(16)00172-8↗
- BackgroundPulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer. DOI 10.1158/0008-5472.can-15-0296↗
- BackgroundUltrasound Guided High Intensity Focused Ultrasound for malignant tumors: The Spanish experience of survival advantage … DOI 10.1016/j.ultsonch.2015.05.026↗
- BackgroundDynamic contrast-enhanced ultrasonographic (DCE-US) assessment of the early response after combined gemcitabine and HIF… DOI 10.1007/s00330-014-3260-4↗
- BackgroundPulsed high-intensity focused ultrasound enhances apoptosis of pancreatic cancer xenograft with gemcitabine. DOI 10.1016/j.ultrasmedbio.2013.06.004↗
- BackgroundFocused ultrasound-mediated drug delivery to pancreatic cancer in a mouse model. DOI 10.1186/2050-5736-1-11↗
- BackgroundFOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. DOI 10.1056/nejmoa1011923↗
- BackgroundConcurrent chemotherapy and pulsed high-intensity focused ultrasound therapy for the treatment of unresectable pancreat… DOI 10.3348/kjr.2011.12.2.176↗