Clinical trialPhase 1 / Phase 2Unknown
Evaluation of the Safety and Efficacy of Esperanza Extract (PA001)
Evaluation of the Safety and Efficacy of Esperanza Extract (Petiveria Alliacea) in Patients With Metastatic Gastrointestinal Tumors and Acute Leukemia
- Outcome
- Outcome unknown
- Phase
- Phase 1 / Phase 2
- Status
- Unknown
- Study type
- Interventional
- Start
- 15 December 2022
- Expected end
- 15 June 2023
- Enrollment
- 82 participants
- Sites
- 1
- Primary outcomes
- Safety and efficacy
- Sponsor
- Other
- Results posted
- No
- Last update
- 19 October 2022
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Papers 25
- Builds on itExploring the safety and efficacy of phytomedicine Petiveria alliacea extract (Esperanza) in patients with metastatic g… DOI 10.1186/s12906-023-04109-2↗
- BackgroundThe metabolism of cancer cells during metastasis. DOI 10.1038/s41568-020-00320-2↗
- BackgroundEvaluation of chemotherapy and P2Et extract combination in ex-vivo derived tumor mammospheres from breast cancer patien… DOI 10.1038/s41598-020-76619-9↗
- BackgroundLipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention. DOI 10.1016/j.addr.2020.07.013↗
- BackgroundReprogramming of fatty acid metabolism in cancer. DOI 10.1038/s41416-019-0650-z↗
- BackgroundExposing the Underlying Relationship of Cancer Metastasis to Metabolism and Epithelial-Mesenchymal Transitions. DOI 10.1016/j.isci.2019.10.060↗
- BackgroundMitochondrial determinants of chemoresistance. DOI 10.20517/cdr.2019.46↗
- BackgroundThe enhancement of glycolysis regulates pancreatic cancer metastasis. DOI 10.1007/s00018-019-03278-z↗
- BackgroundA mechanism for increased sensitivity of acute myeloid leukemia to mitotoxic drugs. DOI 10.1038/s41419-019-1851-3↗
- BackgroundReprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy. DOI 10.1186/s13046-018-0710-x↗
- BackgroundLipid degradation promotes prostate cancer cell survival. DOI 10.18632/oncotarget.16123↗
- BackgroundTumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis. DOI 10.1016/j.tcb.2017.03.003↗
- BackgroundMitochondria and cancer chemoresistance. DOI 10.1016/j.bbabio.2017.01.012↗
- BackgroundHigh Expression of PHGDH Predicts Poor Prognosis in Non-Small Cell Lung Cancer. DOI 10.1016/j.tranon.2016.08.003↗
- BackgroundResistance to chemotherapy is associated with altered glucose metabolism in acute myeloid leukemia. DOI 10.3892/ol.2016.4600↗
- BackgroundInhibition of LDHA suppresses tumor progression in prostate cancer. DOI 10.1007/s13277-015-3540-x↗
- BackgroundMitochondrial uncoupling protein 2 and pancreatic cancer: a new potential target therapy. DOI 10.3748/wjg.v21.i11.3232↗
- BackgroundAML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabol… DOI 10.1182/blood-2014-08-594408↗
- BackgroundBreast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. DOI 10.1038/ncb3094↗
- BackgroundA novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. DOI 10.1002/emmm.201302734↗
- BackgroundHIF-1α and GLUT1 gene expression is associated with chemoresistance of acute myeloid leukemia. DOI 10.7314/apjcp.2014.15.4.1823↗
- BackgroundNovel role of NOX in supporting aerobic glycolysis in cancer cells with mitochondrial dysfunction and as a potential ta… DOI 10.1371/journal.pbio.1001326↗
- BackgroundThe level of glycolytic metabolism in acute myeloid leukemia blasts at diagnosis is prognostic for clinical outcome. DOI 10.1189/jlb.0710417↗
- BackgroundA chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. DOI 10.1016/j.cell.2010.02.027↗
- BackgroundFatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma. DOI 10.1016/j.humpath.2005.11.022↗