Pancreatic Cancer Research

Clinical trialPhase 2Recruiting

A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer

Outcome
Ongoing
Phase
Phase 2
Status
Recruiting
Study type
Interventional
Start
8 November 2023
Expected end
December 2028
Enrollment
25 participants
Sites
2
Primary outcomes
Change in Immune response rate as assessed by density of intratumoral granzyme B+ CD137+ T cells; Pathologic Response Rate as assessed by number of patients with a grade 0-2 pathologic response
Sponsor
Other
Results posted
No
Last update
7 October 2026

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Brief summary public domain (ClinicalTrials.gov)

The purpose of this study is to evaluate the safety and clinical activity of tislelizumab (an anti-PD-1 antibody) in combination with SX-682 (a CXCR1/2 inhibitor) in subjects with newly diagnosed and surgically resectable pancreatic adenocarcinoma.