Clinical trialNo phase (not a drug trial)Recruiting
The Value of Molecular Residual Disease Monitoring Based on ctDNA in Borderline Resectable or Locally Advanced Pancreatic Cancer
- Outcome
- Ongoing
- Phase
- No phase (not a drug trial)
- Status
- Recruiting
- Study type
- Interventional
- Start
- 1 February 2023
- Expected end
- 1 February 2030
- Enrollment
- 100 participants
- Sites
- 1
- Primary outcomes
- Resection rate
- Sponsor type
- Academic / other
- Results posted
- No
- Last update
- 12 April 2023
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Brief summary public domain (ClinicalTrials.gov)
The goal of this clinical trial is to explore the value of molecular residual disease (MRD) monitoring based on ctDNA in borderline resectable or locally advanced pancreatic cancer. The main questions it aims to answer are: * prognostic value of baseline MRD; * the role of MRD dynamic changes after treatment in guiding treatment. Peripheral blood derived from participants will be obtained for MRD test before conversion therapy initiation and at the first imaging assessment after chemotherapy.