Pancreatic Cancer Research

Clinical trialNACompleted

18F-FAPI PET Imaging in Pancreatic Adenocarcinoma

18F-FAPI PET/CT and 18F-FDG PET/CT in Patients With Pancreatic Adenocarcinoma : A Prospective, Single-Center, Comparative Study

Outcome
Finished, no results posted
Phase
NA
Status
Completed
Study type
Interventional
Start
1 April 2021
Expected end
28 February 2023
Enrollment
62 participants
Sites
1
Primary outcomes
Diagnostic value; Maximum standardized uptake value
Sponsor
Other
Results posted
No
Last update
1 June 2023

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Brief summary public domain (ClinicalTrials.gov)

To explore the potential efficacy of 18F-FAPI-04 PET/CT for PDAC tumour staging and compare the results with those obtained using 18F-FDG PET/CT.

Detailed description public domain (ClinicalTrials.gov)

Accurate diagnosis and staging are crucial for selecting treatment for patients with pancreatic ductal adenocarcinoma (PDAC). The desmoplastic responses associated with PDAC are often characterised by hypometabolism. Here we investigated 18F-fibroblast activation protein inhibitor (18F-FAPI-04) positron emission tomography/computed tomography (PET/CT) in evaluation of PDAC, and compared the findings with those obtained using (18F)-fluorodeoxyglucose (18F-FDG).