Clinical trialPhase 2Recruiting
Tripegfilgrastim Trial to Reduce the Risk of Severe Neutropenia in Patients With Unresectable Pancreaticobiliary Cancers
An Open-label, Randomized, Multicenter, Phase II Tripegfilgrastim Trial to Reduce the Risk of Severe Neutropenia in Patients With Unresectable Pancreaticobiliary Cancers
- Outcome
- Ongoing
- Phase
- Phase 2
- Status
- Recruiting
- Study type
- Interventional
- Start
- 16 January 2024
- Expected end
- 30 June 2026
- Enrollment
- 98 participants
- Sites
- 1
- Primary outcomes
- Primary endpoint
- Sponsor
- Other gov
- Results posted
- No
- Last update
- 18 June 2025
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Papers 13
- BackgroundA real-world analysis of nanoliposomal-irinotecan with 5-fluorouracil and folinic acid as third- or later-line therapy … DOI 10.1177/17588359221119539↗
- BackgroundImpact of G-CSF Prophylaxis on Chemotherapy Dose-Intensity, Link Between Dose-Intensity and Survival in Patients with M… DOI 10.1093/oncolo/oyac055↗
- BackgroundDistinct prognosis of biliary tract cancer according to tumor location, stage, and treatment: a population-based study. DOI 10.1038/s41598-022-13605-3↗
- BackgroundLiposomal irinotecan plus fluorouracil and leucovorin versus fluorouracil and leucovorin for metastatic biliary tract c… DOI 10.1016/s1470-2045(21)00486-1↗
- BackgroundA phase II study of FOLFIRINOX with primary prophylactic pegfilgrastim for chemotherapy-naïve Japanese patients with me… DOI 10.1007/s10147-021-02001-y↗
- BackgroundPrimary Granulocyte Colony-Stimulating Factor Prophylaxis in Metastatic Pancreatic Cancer Patients Treated with FOLFIRI… DOI 10.3390/cancers12113137↗
- BackgroundReal-world efficacy and safety of liposomal irinotecan plus fluorouracil/leucovorin in patients with metastatic pancrea… DOI 10.1177/1758835919871126↗
- BackgroundGemcitabine, Cisplatin, and nab-Paclitaxel for the Treatment of Advanced Biliary Tract Cancers: A Phase 2 Clinical Tria… DOI 10.1001/jamaoncol.2019.0270↗
- BackgroundNab-Paclitaxel and Gemcitabine as First-line Treatment of Advanced or Metastatic Cholangiocarcinoma: A Phase 2 Clinical… DOI 10.1001/jamaoncol.2018.3277↗
- BackgroundNanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-… DOI 10.1016/s0140-6736(15)00986-1↗
- BackgroundPhase III placebo-controlled, double-blind, randomized trial of pegfilgrastim to reduce the risk of febrile neutropenia… DOI 10.1007/s00520-014-2597-1↗
- BackgroundSome aspects of monoamine oxidase pharmacology. DOI 10.1002/cbf.290040204↗
- BackgroundA multiple testing procedure for clinical trials. DOI 10.2307/2530245↗