Pancreatic Cancer Research

Clinical trialObsRecruiting

Early-stage Detection of LIver, Biliary TRAct and PancReatic Cancers

Early-stage Detection of LIver, Biliary TRAct and PancReatic Cancers by Liquid BiopsY in Periphheral Blood: a Prospective Study (LIBRARY Study)

Outcome
Ongoing
Phase
Obs
Status
Recruiting
Study type
Observational
Start
1 November 2023
Expected end
31 December 2025
Enrollment
1,608 participants
Sites
1
Primary outcomes
The sensitivity and specificity of the cfDNA methylation model in detection of liver, biliary tract and pancreatic cancers.
Sponsor
Other
Results posted
No
Last update
10 February 2025

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Brief summary public domain (ClinicalTrials.gov)

LIBRARY is a prospective, multi-center, observational study aimed at detecting early liver, biliary tract, and pancreatic cancers by combining assays of cell-free DNA (cfDNA) methylation, serum protein, and microRNA.

Detailed description public domain (ClinicalTrials.gov)

LIBRARY is a prospective, multi-center, observational study aimed at detecting early liver, biliary tract, and pancreatic cancers by combining assays of cell-free DNA (cfDNA) methylation, serum protein, and microRNA. The study will enroll approximately 458 participants diagnosed with liver, biliary tract, and pancreatic cancers, 330 individuals with corresponding benign diseases and 820 healthy participants.