Pancreatic Cancer Research

Clinical trialPhase 2Terminated

A Study of Surufatinib as Adjuvant Therapy for Pancreatic Neuroendocrine Tumors

A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Trial of Surufatinib as Adjuvant Therapy for Pancreatic Neuroendocrine Tumors

Outcome
Stopped earlyThis investigator-initiated study closed to recruitment early due to slower-than-anticipated patient accrual. (Enrollment)
Phase
Phase 2
Status
Terminated
Study type
Interventional
Start
17 June 2024
Ended
9 June 2026
Enrollment
6 participants
Sites
1
Primary outcomes
2-year disease-free survival (2y-DFS)
Sponsor type
Academic / other
Results posted
No
Last update
11 June 2026

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Brief summary public domain (ClinicalTrials.gov)

pNENs still have a risk of recurrence after radical resection, and the overall recurrence and metastasis rate is as high as 13.7%-36.2% in China. At present, there is no standard adjuvant therapy for pNEN, and prospective studies are still lacking. This study was a randomized, double-blind, placebo-controlled, multicenter clinical trial to explore the efficacy and safety of surufatinib in the adjuvant treatment of pNET, in order to further improve the prognosis of patients and to provide high-quality research evidence for adjuvant therapy.