Clinical trialNAUnknown
Celiac plExus Block to Reduce OpioID Consumption Following Hepato-pancreato-biliary Mini-invasive Surgery
Celiac Plexus Block to Reduce Opioid Consumption Following Hepato-pancreato-biliary Mini-invasive Surgery: a Randomized Controlled Trial
- Outcome
- Outcome unknown
- Phase
- NA
- Status
- Unknown
- Study type
- Interventional
- Start
- 1 March 2024
- Expected end
- 31 December 2025
- Enrollment
- 60 participants
- Sites
- 0
- Primary outcomes
- Postoperative opioid use
- Sponsor
- Other
- Results posted
- No
- Last update
- 19 January 2024
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Source text
Brief summary public domain (ClinicalTrials.gov)
The goal of this study is to assess the efficacy of intraoperative celiac plexus block (CPB) to reduce opioid consumption following laparoscopic hepato-pancreato-biliary surgery
Detailed description public domain (ClinicalTrials.gov)
A bilateral CPB is convenient and safe to perform under the direct laparoscopic vision of the surgeons during surgery; however, perspective data are warranted. The investigators hypothesize that a bilateral CPB using 0.5% ropivacaine will improve the quality of recovery following a laparoscopic hepato-pancreato-biliary surgery. The primary endpoint is the Postoperative opioid use. Secondary endpoints include acute postoperative pain, opioid consumption, the incidence of postoperative nausea or vomiting (PONV), the 15-item quality of recovery questionnaire (QoR-15), length of post-anesthesia care unit (PACU) stay, length of post-operative hospital stay, and chronic post-surgical pain at 90 d after surgery.
Papers 5
- BackgroundInterventional Therapy for Pancreatic Cancer. DOI 10.1159/000446800↗
- BackgroundMRI-guided celiac plexus neurolysis for pancreatic cancer pain: Efficacy and safety. DOI 10.1002/jmri.25246↗
- BackgroundA prospective, randomized, double-blind, placebo controlled trial on the efficacy of ethanol celiac plexus neurolysis i… DOI 10.1016/j.jamcollsurg.2014.12.013↗
- BackgroundRandomized, double-blind, controlled trial of early endoscopic ultrasound-guided celiac plexus neurolysis to prevent pa… DOI 10.1200/jco.2010.32.2750↗
- BackgroundProspective evaluation of laparoscopic celiac plexus block in patients with unresectable pancreatic adenocarcinoma. DOI 10.1245/s10434-010-1372-x↗