Pancreatic Cancer Research

Clinical trialObsRecruiting

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

Outcome
Ongoing
Phase
Obs
Status
Recruiting
Study type
Observational
Start
12 December 2024
Expected end
1 November 2029
Enrollment
30,000 participants
Sites
11
Primary outcomes
Develop a biobank of biospecimens and data of subjects without pancreatic cancer who are at high risk for pancreatic cancer; Follow subjects longitudinally and collect biospecimens and follow-up data and record medical outcomes
Sponsor
Other
Results posted
No
Last update
21 September 2026

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Brief summary public domain (ClinicalTrials.gov)

This study evaluates individuals without pancreatic cancer, but who have been determined to be at higher-than-average lifetime risk of developing pancreatic cancer to help detect pancreatic cancer or other cancers at an earlier time when they might be more easily treated and cured.

Detailed description public domain (ClinicalTrials.gov)

PRIMARY OBJECTIVES: I. To develop a cohort (biobank of biospecimens and data) of subjects without pancreatic cancer who are at highrisk for pancreatic cancer due to: a strong family history, a mutation in a known pancreatic cancer predisposition gene, or fukuoka worrisome or high-risk pancreatic cysts. II. To follow the cohort subjects longitudinally and collect biospecimens and follow-up data and record medical outcomes. III. To make biospecimen available to PCDC-approved projects to validate potential biomarkers for performance using nested case-control prospective designs. OUTLINE: This is an observational study. Participants undergo blood sample collection, complete questionnaires, have their medical records reviewed and undergo pancreatic cyst fluid collection during standard of care endoscopic ultrasounds fine needle aspiration.