Pancreatic Cancer Research

Clinical trialPhase 1Completed

Irreversible Electroporation & Pembro Immunotherapy in Locally Advanced Pancreatic Cancer

A Phase 1 Study of Irreversible Electroporation and Pembrolizumab Immunotherapy in Locally Advanced Pancreatic Cancer

Outcome
Finished, no results posted
Phase
Phase 1
Status
Completed
Study type
Interventional
Start
10 April 2024
Expected end
15 September 2025
Enrollment
2 participants
Sites
1
Primary outcomes
Safety and Tolerability
Sponsor
Other
Results posted
No
Last update
9 February 2026

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Brief summary public domain (ClinicalTrials.gov)

This study aims to determine the safety and tolerability of combining sequential therapy of Irreversible Electroporation (IRE) and Immunotherapy (IO) for patients with locally advanced unresectable pancreas cancer following first-line treatment with chemotherapy and ablative stereotactic magnetic resonance image-guided adaptive radiation therapy (A-SMART).