Pancreatic Cancer Research

Clinical trialPhase 2Recruiting

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

A Phase 2 Single Arm Trial of Stereotactic Body Radiation Therapy Followed by Dual Immune Checkpoint Inhibition for Patients With Metastatic Pancreatic Ductal Adenocarcinoma - The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

Outcome
Ongoing
Phase
Phase 2
Status
Recruiting
Study type
Interventional
Start
18 June 2025
Expected end
1 August 2030
Enrollment
20 participants
Sites
1
Primary outcomes
Clinical Benefit Rate (CBR)
Sponsor
Other
Results posted
No
Last update
21 August 2026

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Brief summary public domain (ClinicalTrials.gov)

The purpose of this study is to assess if radiation therapy (which uses high-energy radiation to damage or destroy cancer cells) combined with immune checkpoint inhibitors (medications that helps the body recognize and attack cancer cells) will be beneficial for patients with metastatic pancreatic ductal adenocarcinoma.