Clinical trialEarly Phase 1Recruiting
Exploratory Clinical Study of Targeted Activated DC and CAR-T Therapy in Advanced Solid Cancers
Exploratory Clinical Study of Targeted Activated DC and CAR-T Therapy in Patients With Advanced Solid Cancers.
- Outcome
- Ongoing
- Phase
- Early Phase 1
- Status
- Recruiting
- Study type
- Interventional
- Start
- 6 December 2025
- Expected end
- 6 June 2028
- Enrollment
- 10 participants
- Sites
- 1
- Primary outcomes
- Adverse Events (AEs)
- Sponsor type
- Academic / other
- Results posted
- No
- Last update
- 16 March 2026
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Brief summary public domain (ClinicalTrials.gov)
This is an open-label, single-arm clinical study designed to evaluate the safety and preliminary efficacy of Targeted Activated DC combined with CAR-T therapy in patients with Advanced Solid Cancers.This combination therapy activates dendritic cells (DCs) to precisely target the tumor site, reshaping the tumor immune microenvironment, breaking down the immunosuppressive barrier, and allowing CAR-T cells to penetrate deeper into the tumor more efficiently, precisely and persistently killing cancer cells.