Seven findings from the claudin 18.2 research record

Computed from 49 clinical trials, 63 papers and 1 NIH grants as the records stand on 2 Nov 2026. Hover a figure for its values, click a trial or paper to open the record, or ask a follow-up question.

Trial starts peaked in 2025, with 11 of the 49 claudin 18.2 trials in the record.

Phase 1Phase 2Phase 3Phase not stated

14 of 29 Claudin 18.2 trials are CLDN18.2 cell therapy & bispecifics.

24 of 49 trials are recruiting patients now; two have posted results.

RecruitingNot yet recruitingActive, not recruitingStopped earlyOther status

The 40 most recent starts are shown; 9 earlier trials are left off.

Four trials account for 56% of the 476 places where patients can enroll; 29 of 49 run at one site or have none listed yet.

RecruitingActive, not recruitingCompleted

122 of the 416 research places in the record are in the United States; Peking University Cancer Hospital hosts the most trials, six.

132 places on this map

Memorial Sloan Kettering Cancer Center5
Medical College of Wisconsin4
City of Hope3
The University of Texas MD Anderson Cancer Center3
Moffitt Cancer Center2
Roswell Park Comprehensive Cancer Center2
Washington University in St. Louis2
Emory University2
The University of Kansas Cancer Center2

Outside this map: 119 in China, 26 in France, 23 in Japan, 23 in Spain, 17 in South Korea, 13 in Italy, 9 in TW, 7 in Australia, 6 in Germany, 6 in United Kingdom, 5 in MY, 5 in BR, 5 in TURKEY (TÜRKIYE), 3 in Netherlands, 2 in TR, 2 in PL, 2 in BE, 2 in MX, 1 in HR, 1 in SE, 1 in OM, 1 in CZ, 1 in SG, 1 in GEORGIA, 1 in PR, 1 in MOLDOVA.

Claudin 18.2 saw papers or trials in eight years and NIH money in one; they coincide in one.

Papers or trials, no NIH dollarsNIH dollars, no papers or trialsBoth

Each square is one topic in one year. Blue years produced work with no new NIH money behind it; amber years were funded but produced no paper or trial that year.

Grants pay out over several years and results lag funding, so a gap here is a question to ask, not a verdict. Switch the view to see dollars or output alone.

Source: NIH RePORTER (National Institutes of Health, NIAAA, NIA, NIAID, NIAMS, NCCIH, NCI (intramural), NIH BX, NCI, NIH Clinical Center, NIH CP, NIH CX, NIDCR, NIDDK, NIBIB, NIEHS, NEI, NIH FD, NIGMS, NICHD, NHGRI, NHLBI, NIH HX, NLM, NIMHD, NIMH, NINDS, NIH OD, NIH RD, NCRR, NCI (intramural), NCATS, FIC, Congressionally Directed Medical Research Programs - Pancreatic Cancer Research Program, Lustgarten Foundation, Pancreatic Cancer Action Network) against Europe PMC papers and ClinicalTrials.gov starts.

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