Seven findings from the KRAS G12D research record

Computed from 62 clinical trials, 787 papers and 36 NIH grants as the records stand on 2 Nov 2026. Hover a figure for its values, click a trial or paper to open the record, or ask a follow-up question.

Trial starts peaked in 2026, with 21 of the 61 KRAS G12D trials in the record.

Phase 1Phase 2Phase 3

41 of 60 KRAS G12D trials are G12D-targeted.

36 of 61 trials are recruiting patients now; three have posted results.

RecruitingNot yet recruitingActive, not recruitingStopped early

The 40 most recent starts are shown; 21 earlier trials are left off.

Six trials account for 53% of the 921 places where patients can enroll; 25 of 62 run at one site or have none listed yet.

RecruitingActive, not recruitingStopped early

421 of the 979 research places in the record are in the United States; The University of Texas MD Anderson Cancer Center hosts the most trials, 19.

434 places on this map

The University of Texas MD Anderson Cancer Center46
Memorial Sloan Kettering Cancer Center18
Fred and Pamela Buffett Cancer Center18
Johns Hopkins University15
University of Michigan14
University of California, Los Angeles14
Mayo Clinic12
University of Miami12
Northwestern University12

Outside this map: 111 in China, 49 in Germany, 47 in France, 46 in Japan, 43 in Spain, 35 in Italy, 29 in Australia, 27 in United Kingdom, 27 in South Korea, 16 in TW, 15 in BE, 12 in IL, 11 in PL, 7 in CH, 7 in IN, 7 in AT, 6 in Denmark, 6 in Netherlands, 6 in GEORGIA, 5 in NO, 4 in SE, 4 in PR, 3 in HK, 3 in SG, 3 in NZ, 2 in FI, 1 in HU, 1 in EG, 1 in PT, 1 in TH, 1 in ZA, 1 in GR, 1 in MO, 1 in BN, 1 in CZ, 1 in CO, 1 in QA, 1 in IE, 1 in BR, 1 in United States.

KRAS G12D saw papers or trials in 16 years and NIH money in 13; they coincide in 13.

Papers or trials, no NIH dollarsNIH dollars, no papers or trialsBoth

Each square is one topic in one year. Blue years produced work with no new NIH money behind it; amber years were funded but produced no paper or trial that year.

Grants pay out over several years and results lag funding, so a gap here is a question to ask, not a verdict. Switch the view to see dollars or output alone.

Source: NIH RePORTER (National Institutes of Health, NIAAA, NIA, NIAID, NIAMS, NCCIH, NCI (intramural), NIH BX, NCI, NIH Clinical Center, NIH CP, NIH CX, NIDCR, NIDDK, NIBIB, NIEHS, NEI, NIH FD, NIGMS, NICHD, NHGRI, NHLBI, NIH HX, NLM, NIMHD, NIMH, NINDS, NIH OD, NIH RD, NCRR, NCI (intramural), NCATS, FIC, Congressionally Directed Medical Research Programs - Pancreatic Cancer Research Program, Lustgarten Foundation, Pancreatic Cancer Action Network) against Europe PMC papers and ClinicalTrials.gov starts.

Ask about this →